Introducing Fluidity One
Characterisation 100% in solution
No surfaces or matrices
More robust, relevant results
Microlitre sample requirements
Sample to results quickly
Access your data in the cloud
Minimal sample prep
Modern, Android-based user interface
Simple, standardisable workflows
The Fluidity One-W uses microfluidic diffusional sizing in combination with visible wavelength detection to determine the hydrodynamic radius of a single species of protein in solution, even in complex mixtures such as cell lysates, using small sample volumes.
The Fluidity One-I combines diffusional sizing with immuno-labelling to selectively size and quantify chosen targets on a disposable chip
MDS chips are supplied in multiples of 5 boxes (120 chips), and bundled with a reagent cartridge sufficient for their use.
Includes our latent amine reactive label to ensure high sensitivity and low background
|Instrument||Fluidity One||Fluidity One-W|
|What does it do?||In-solution sizing and quantification of native protein in as little as 6 minutes||High sensitivity in-solution analysis of changes in protein size for the study of interaction kinetics|
|Measurement||Microfluidic diffusional sizing||Microfluidic diffusional sizing|
|Detection approach||Introduction of latent amine-reactive dye post measurement||Excitation of pre-labelled fluorescent proteins and biomolecules|
|Learn more||Learn more|
Rather than labelling the total protein with an amine-reactive dye, or pre-labelling proteins with a fluorophore, we are currently exploring options for immuno-labelling on the chip, such that single species can be detected post-measurement.
To address the demand for sizing tens of samples (or more) in an automated manner, we are combining the Fluidity One with liquid handling capabilities. We are seeking partners interested in a commercial version of this instrument.